Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 1/20 | 0.57 |
| ▸ | DAO | P14920 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | PHGDH | O43175 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | BRD4 | O60885 | 1/20 | 0.46 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.46 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.46 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27852170 | 0.90 | MCL1 (0.57) | MCL1DAOKMT2APHGDHCA12 | |
| SCHEMBL6188130 | 0.84 | MCL1 (0.51) | MCL1DAOKMT2APHGDHSLC9A1 | |
| SCHEMBL21807358 | 0.83 | MCL1 (0.57) | MCL1DAOKMT2APHGDHCA12 | |
| SCHEMBL31291305 | 0.80 | MCL1 (0.53) | MCL1DAOKMT2APHGDHCA12 | |
| SCHEMBL11600616 | 0.80 | MCL1 (0.53) | MCL1DAOKMT2APHGDHCA12 | |
| SCHEMBL9887744 | 0.80 | KMT2A (0.55) | MCL1DAOKMT2APHGDHCA12 | |
| SCHEMBL9565143 | 0.77 | KMT2A (0.52) | MCL1DAOKMT2ACA12BRD4 | |
| SCHEMBL20746874 | 0.77 | KMT2A (0.52) | MCL1DAOKMT2APHGDHCA12 | |
| SCHEMBL18358089 | 0.76 | MCL1 (0.50) | MCL1DAOKMT2APHGDHSLC9A1 | |
| SCHEMBL27852172 | 0.76 | MCL1 (0.49) | MCL1DAOKMT2APHGDHCA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5017584-A | Antidepressant 2-(4,5-dihydro-1H-imidazolyl)-dihydro-1H-indoles, -1,2,3,4-tetrahydroquinolines and -1H-indoles, and methods of use thereas | STERLING DRUG INC. (US) | 1991-05-21 | — | — | US | disclosed |