Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN1A | P35498 | 2/20 | 0.44 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.44 |
| ▸ | SCN3A | Q9NY46 | 2/20 | 0.44 |
| ▸ | CXCR4 | P61073 | 6/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.40 |
| ▸ | MAOB | P27338 | 2/20 | 0.40 |
| ▸ | HRH2 | P25021 | 1/20 | 0.40 |
| ▸ | HRH1 | P35367 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20143214 | 0.90 | SCN1A (0.51) | SCN1ASCN2ASCN3ACXCR4HRH3 | |
| SCHEMBL23206108 | 0.78 | HRH3 (0.45) | SCN1ASCN2ASCN3ACXCR4HRH3 | |
| SCHEMBL14207965 | 0.78 | HRH3 (0.45) | SCN1ASCN2ASCN3ACXCR4HRH3 | |
| SCHEMBL23205030 | 0.78 | HRH3 (0.45) | SCN1ASCN2ASCN3ACXCR4HRH3 | |
| SCHEMBL5253867 | 0.78 | KCNK3 (0.36) | — | |
| SCHEMBL18768683 | 0.77 | CXCR4 (0.51) | CXCR4HRH3 | |
| SCHEMBL2553573 | 0.77 | CXCR4 (0.46) | SCN1ASCN2ASCN3ACXCR4HRH3 | |
| SCHEMBL9868824 | 0.76 | SCN1A (0.44) | SCN1ASCN2ASCN3ACXCR4HRH3 | |
| SCHEMBL22142939 | 0.75 | HRH3 (0.45) | SCN1ASCN2ASCN3ACXCR4HRH3 | |
| SCHEMBL22142846 | 0.75 | HRH3 (0.45) | SCN1ASCN2ASCN3ACXCR4HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991011448-A1 | THERAPEUTIC AGENTS | THE BOOTS COMPANY PLC (GB) | 1991-08-08 | — | — | WO | disclosed |