Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.52 |
| ▸ | IDO1 | P14902 | 2/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.44 |
| ▸ | DAO | P14920 | 3/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.41 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | XIAP | P98170 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 2/20 | 0.39 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.39 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1822739 | 0.81 | IDO1 (0.58) | TAAR1IDO1FFAR4MAOB | |
| SCHEMBL19554068 | 0.79 | TAAR1 (0.57) | TAAR1IDO1HRH3DAO | |
| SCHEMBL2095453 | 0.79 | TAAR1 (0.52) | TAAR1IDO1DAOALOX5MAOB | |
| SCHEMBL2095678 | 0.79 | TAAR1 (0.52) | TAAR1IDO1DAOALDH1A1 | |
| SCHEMBL5546013 | 0.79 | MAOB (0.53) | MAOB | |
| SCHEMBL5545075 | 0.78 | MAPT (0.38) | ALDH1A1 | |
| SCHEMBL5543943 | 0.77 | AGXT (0.47) | GPR84FFAR4 | |
| SCHEMBL10204841 | 0.77 | TAAR1 (0.59) | TAAR1IDO1HRH3DAOALOX5 | |
| SCHEMBL26582 | 0.77 | CA1 (0.48) | TAAR1IDO1ALDH1A1HCAR2 | |
| SCHEMBL29596752 | 0.76 | TAAR1 (0.74) | TAAR1IDO1HRH3DAOGPR84 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991011448-A1 | THERAPEUTIC AGENTS | THE BOOTS COMPANY PLC (GB) | 1991-08-08 | — | — | WO | disclosed |