Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.47 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | CA12 | O43570 | 2/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | ANPEP | P15144 | 1/20 | 0.33 |
| ▸ | ENPEP | Q07075 | 1/20 | 0.33 |
| ▸ | MGAM | O43451 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | SI | P14410 | 1/20 | 0.33 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8399384 | 0.88 | TSHR (0.50) | TSHRSLC1A1HSD17B10KMT2AMEN1 | |
| SCHEMBL8462380 | 0.78 | FOLH1 (0.54) | SLC1A1LMNAFOLH1ANPEPENPEP | |
| SCHEMBL5749928 | 0.78 | TSHR (0.48) | TSHRSLC1A1KMT2AMEN1LMNA | |
| SCHEMBL3872540 | 0.78 | TSHR (0.48) | TSHRSLC1A1KMT2AMEN1LMNA | |
| SCHEMBL10929135 | 0.76 | — | — | |
| SCHEMBL8472489 | 0.76 | FOLH1 (0.63) | TSHRSLC1A1FOLH1 | |
| SCHEMBL27910318 | 0.75 | FOLH1 (0.58) | TSHRSLC1A1HSD17B10KMT2AMEN1 | |
| SCHEMBL2865042 | 0.74 | — | — | |
| SCHEMBL21164254 | 0.73 | SLC1A1 (0.45) | TSHRSLC1A1HSD17B10KMT2AMEN1 | |
| SCHEMBL6667904 | 0.73 | SLC22A6 (0.43) | TSHRHSD17B10KMT2AMEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5015656-A | Antidepressants, anxiolytic compounds, central nervous system active compounds for psychotic conditions, aminoalkylcarboxami de derivatives of thiophene | LILLY S.A. (ES) | 1991-05-14 | — | — | US | disclosed |