Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 6/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | TSHR | P16473 | 3/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | ATM | Q13315 | 2/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27791663 | 0.88 | HSD17B10 (0.48) | HSD17B10NAPRTMAPTPOLBTDP1 | |
| SCHEMBL5511994 | 0.87 | CA12 (0.50) | HSD17B10NAPRTMAPTPOLBTDP1 | |
| SCHEMBL10666925 | 0.78 | ATM (0.49) | HSD17B10MAPTTDP1ALDH1A1TSHR | |
| SCHEMBL9155687 | 0.78 | POLB (0.55) | HSD17B10NAPRTMAPTPOLBALDH1A1 | |
| SCHEMBL11404130 | 0.78 | ATM (0.49) | HSD17B10MAPTTDP1ALDH1A1TSHR | |
| SCHEMBL9155698 | 0.78 | POLB (0.55) | HSD17B10NAPRTMAPTPOLBALDH1A1 | |
| SCHEMBL9334531 | 0.75 | CA12 (0.50) | HSD17B10NAPRTMAPTTDP1ALDH1A1 | |
| SCHEMBL33927 | 0.74 | TDP1 (0.56) | HSD17B10NAPRTMAPTPOLBTDP1 | |
| SCHEMBL1331551 | 0.74 | TDP1 (0.56) | HSD17B10NAPRTMAPTPOLBTDP1 | |
| SCHEMBL33928 | 0.74 | TDP1 (0.56) | HSD17B10NAPRTMAPTPOLBTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5010161-A | Of poly (phenylenebisalkylene) poly (phenylamine) with aldehyde, regenerated under hydrolysis, for use in moisture curable polyurethanes | MITSUI TOATSU CHEMICALS, INC. (JP) | 1991-04-23 | — | — | US | disclosed |
| EP-0375318-A2 | Polyaldimine derivatives | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1990-06-27 | — | — | EP | disclosed |