Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 5/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 5/20 | 0.53 |
| ▸ | MAPT | P10636 | 8/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.41 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10374437 | 1.00 | DHODH (0.55) | DHODHNPSR1MAPTALDH1A1MEN1 | |
| SCHEMBL9870075 | 1.00 | DHODH (0.55) | DHODHNPSR1MAPTALDH1A1MEN1 | |
| SCHEMBL10372641 | 0.92 | DHODH (0.54) | DHODHNPSR1MAPTALDH1A1MEN1 | |
| SCHEMBL10372640 | 0.92 | DHODH (0.54) | DHODHNPSR1MAPTALDH1A1MEN1 | |
| SCHEMBL9204037 | 0.91 | DHODH (0.57) | DHODHNPSR1MAPTALDH1A1MEN1 | |
| SCHEMBL9562413 | 0.91 | DHODH (0.57) | DHODHNPSR1MAPTALDH1A1MEN1 | |
| SCHEMBL9381550 | 0.85 | DHODH (0.54) | DHODHNPSR1MAPTALDH1A1MEN1 | |
| SCHEMBL9381551 | 0.85 | DHODH (0.54) | DHODHNPSR1MAPTALDH1A1MEN1 | |
| SCHEMBL19728797 | 0.84 | MEN1 (0.45) | DHODHNPSR1MAPTALDH1A1MEN1 | |
| SCHEMBL7502747 | 0.84 | DHODH (0.53) | DHODHNPSR1MAPTALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4981854-A | BACTERICIDES, ANIMAL GROWTH REGUALTORS | BAYER AKTIENGESELLSCHAFT (DE) | 1991-01-01 | — | — | US | disclosed |
| US-4980353-A | BACTERICIDES, ANIMAL GROWTH REGULATORS | BAYER AKTIENGESELLSCHAFT (DE) | 1990-12-25 | — | — | US | disclosed |
| EP-0154780-B1 | QUINOLINE ANTIBACTERIAL COMPOUNDS | ABBOTT LABORATORIES (US) | 1990-04-11 | — | — | EP | disclosed |
| EP-0201829-A1 | 1-Aryl-4-quinolone-3-carboxylic acids | BAYER AG (DE) | 1986-11-20 | — | — | EP | disclosed |
| EP-0154780-A1 | Quinoline antibacterial compounds | ABBOTT LABORATORIES (US) | 1985-09-18 | — | — | EP | disclosed |