Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SGMS2 | Q8NHU3 | 2/20 | 0.44 |
| ▸ | MAPK14 | Q16539 | 6/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | BRD4 | O60885 | 1/20 | 0.42 |
| ▸ | ALPG | P10696 | 1/20 | 0.42 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.42 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.41 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.41 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.41 |
| ▸ | LIPE | Q05469 | 1/20 | 0.41 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.40 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.40 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.40 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.40 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2115729 | 0.78 | MAPK14 (0.51) | MAPK14MEN1ALDH1A1HPGDHTT | |
| Propionic Acid SCHEMBL28565391 | 0.76 | MAPK14 (0.42) | MAPK14MEN1ALDH1A1HPGDHTT | |
| SCHEMBL10671051 | 0.76 | MAPK14 (0.47) | MAPK14MEN1ALDH1A1HPGDHTT | |
| SCHEMBL17695114 | 0.75 | MAPK14 (0.41) | MAPK14MEN1ALDH1A1HPGDHTT | |
| SCHEMBL27937365 | 0.75 | COMT (0.49) | MAPK14MEN1ALDH1A1HPGDHTT | |
| SCHEMBL28378443 | 0.74 | MAPK14 (0.42) | MAPK14MEN1ALDH1A1HPGDHTT | |
| SCHEMBL17128962 | 0.74 | MAPK14 (0.42) | MAPK14MEN1ALDH1A1HPGDHTT | |
| SCHEMBL29067955 | 0.74 | MAPK14 (0.48) | MAPK14MEN1ALDH1A1HPGDHTT | |
| SCHEMBL23258867 | 0.73 | MAPT (0.59) | SGMS2MAPK14BRD4ALPGPTK2B | |
| SCHEMBL12949898 | 0.72 | MAPK14 (0.41) | MAPK14MEN1ALDH1A1HPGDHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5015737-A | Antibiotics, bactericides | THE UPJOHN COMPANY (US) | 1991-05-14 | — | — | US | disclosed |
| US-4743685-A | 2-oxo-1-[[(substituted sulfonyl)amino]carbonyl]azetidines | E. R. SQUIBB & SONS, INC. (US) | 1988-05-10 | — | — | US | disclosed |