SCHEMBL987055

SCHEMBL987055

CC(=O)N[C@H]1[C@H]([C@H](O)[C@H](O)COP(=O)(O)O)O[C@](O)(C(=O)O)C[C@@H]1O

nearest known ligand 0.73

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
NANP Q8TBE9 3/20 0.73
L3MBTL1 Q9Y468 1/20 0.48
CD22 P20273 2/20 0.36
SIGLEC7 Q9Y286 1/20 0.36
SELL P14151 1/20 0.35
SELP P16109 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27240372 1.00 NANP (0.73) NANPL3MBTL1CD22SIGLEC7SELL
SCHEMBL29397247 1.00 NANP (0.73) NANPL3MBTL1CD22SIGLEC7SELL
SCHEMBL13191000 1.00 NANP (0.73) NANPL3MBTL1CD22SIGLEC7SELL
SCHEMBL30887281 0.87 NANP (0.69) NANPL3MBTL1CD22SIGLEC7SELL
SCHEMBL27240262 0.87 NANP (0.69) NANPL3MBTL1CD22SIGLEC7SELL
Sialic Acid SCHEMBL29668416 0.86 NANP (0.77) NANPL3MBTL1SIGLEC7SELLSELP
Sialic Acid SCHEMBL19718196 0.86 NANP (0.77) NANPL3MBTL1SIGLEC7SELLSELP
Sialic Acid SCHEMBL3156058 0.86 NANP (0.77) NANPL3MBTL1SIGLEC7SELLSELP
SCHEMBL420656 0.86 NANP (0.67) NANPL3MBTL1SELLSELP
SCHEMBL29390472 0.86 NANP (0.67) NANPL3MBTL1SELLSELP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 186 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116773710-A Kit for covering metabolome and metabolic flow of multiple metabolites and use method 清华大学 2023-09-19 CN claimed
CN-116323930-A Cell production of sialylated di-and/or oligosaccharides 因比奥斯公司 2023-06-23 CN claimed
WO-2023057386-A1 COMPOSITIONS FOR PREVENTING AND/OR TREATING DEMYELINATION MJN U.S. HOLDINGS LLC (US) 2023-04-13 WO claimed
CN-113624862-B Metabolome covering multiple metabolites, metabolic flux analysis method and kit 清华大学 2023-04-07 CN claimed
EP-4003365-A1 SIALIC ACID FOR USE IN THE TREATMENT OF PSORIASIS Lifescience AS (NO) 2022-06-01 EP claimed
WO-2022006503-A2 METHODS TO GLYCOENGINEER PROTEINS THE JOHNS HOPKINS UNIVERSITY (US) 2022-01-06 WO claimed
CN-113624862-A Metabolome covering multiple metabolites, metabolic flux analysis method and kit 清华大学 2021-11-09 CN claimed
WO-2021019295-A1 SIALIC ACID FOR USE IN THE TREATMENT OF PSORIASIS REMMEREIT JAN (NO) 2021-02-04 WO claimed
CN-104736694-B CRZ1 mutant fungal cells 默沙东公司 2020-08-11 CN claimed
US-9328367-B2 Engineered lower eukaryotic host strains for recombinant protein expression MERCK SHARP & DOHME CORP. (US) 2016-05-03 US claimed
US-20140024812-A1 ENGINEERED INTRACELLULAR SIALYLATION PATHWAYS THE UNIVERSITY OF WYOMING (US) 2014-01-23 US claimed
US-8546105-B2 Engineering intracellular sialylation pathways THE UNIVERSITY OF WYOMING (US) 2013-10-01 US claimed
WO-2013062940-A1 ENGINEERED LOWER EUKARYOTIC HOST STRAINS FOR RECOMBINANT PROTEIN EXPRESSION MERCK SHARP & DOHME CORP. (US) 2013-05-02 WO claimed
WO-2013019625-A2 METHODS OF USING A BACTERIAL GLCNAC-6-P 2'-EPIMERASE TO PROMOTE SIALYLATION OF GLYCOCONJUGATES THE UNIVERSITY OF WYOMING (US) 2013-02-07 WO claimed
US-20130029413-A1 Methods of Using a Bacterial GlcNAc-6-P 2'- Epimerase to Promote Sialylation of Glycoconjugates UNIVERSITY OF WYOMING (US) 2013-01-31 US claimed
US-20120264928-A1 THERAPEUTIC PHARMACEUTICAL AGENT FOR DISEASES ASSOCIATED WITH DECREASE IN FUNCTION OF GNE PROTEIN, FOOD COMPOSITION, AND FOOD ADDITIVE JAPAN HEALTH SCIENCES FOUNDATION (JP) 2012-10-18 US claimed
US-20110229931-A1 Engineering intracellular sialylation pathways THE UNIVERSITY OF WYOMING 2011-09-22 US claimed
EP-0524143-B1 Process of preparation of activated sialic acids CIBA GEIGY AG (CH) 1997-12-10 EP claimed
US-5334514-A Reacting sialic acid with cytidine 5*-triphosphate in presence of cell extract of microorganism having cytidine 5*-monophospho-N-acetylneuraminic acid synthetase activity CIBA VISION CORPORATION 1994-08-02 US claimed
EP-0524143-A1 Process of preparation of activated sialic acids CIBA-GEIGY AG (CH) 1993-01-20 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120264928-A1 THERAPEUTIC PHARMACEUTICAL AGENT FOR DISEASES ASSOCIATED WITH DECREASE IN FUNCTION OF GNE PROTEIN, FOOD COMPOSITION, AND FOOD ADDITIVE GNE, ENGASE, GNPDA1 NANP 27/4885L3MBTL1 4159/4885CD22 3015/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.