Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.49 |
| ▸ | CTSB | P07858 | 3/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | CTSL | P07711 | 1/20 | 0.40 |
| ▸ | CTSS | P25774 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 2/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.39 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | DAO | P14920 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5110312 | 0.95 | MEN1 (0.57) | MEN1KMT2ATAAR1CTSBHRH3 | |
| SCHEMBL8361121 | 0.90 | MEN1 (0.55) | MEN1KMT2ATAAR1CTSBHRH3 | |
| SCHEMBL6557766 | 0.84 | MEN1 (0.73) | MEN1KMT2ATAAR1HRH3IDO1 | |
| SCHEMBL8099771 | 0.78 | TAAR1 (0.68) | TAAR1HRH3IDO1HDAC3HDAC1 | |
| SCHEMBL8092500 | 0.78 | TAAR1 (0.68) | TAAR1HRH3IDO1DAO | |
| Dimethylamine SCHEMBL9872133 | 0.77 | TAAR1 (0.53) | MEN1KMT2ATAAR1HRH3IDO1 | |
| SCHEMBL1610656 | 0.77 | TAAR1 (0.53) | TAAR1HRH3IDO1HDAC3HDAC1 | |
| SCHEMBL6083770 | 0.77 | TAAR1 (0.53) | TAAR1HRH3IDO1HDAC3HDAC1 | |
| Dimethylamine SCHEMBL9872976 | 0.76 | TAAR1 (0.67) | MEN1KMT2ATAAR1HRH3IDO1 | |
| SCHEMBL8093918 | 0.76 | TAAR1 (0.65) | TAAR1HRH3IDO1HDAC3HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5021429-A | Histamine h2-antagonists; antisecretory-antiallergen agent; skin disorders and peptic ulcers | ALLEN & HANSBURYS LIMITED (GB) | 1991-06-04 | — | — | US | disclosed |