Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PHGDH | O43175 | 2/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | MGLL | Q99685 | 2/20 | 0.44 |
| ▸ | FAAH | O00519 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | ADH1A | P07327 | 4/20 | 0.35 |
| ▸ | ADH1C | P00326 | 3/20 | 0.34 |
| ▸ | FDPS | P14324 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6683780 | 0.85 | PHGDH (0.52) | PHGDHALDH1A1MGLLFAAHCYP3A4 | |
| SCHEMBL1426473 | 0.82 | PHGDH (0.61) | PHGDHALDH1A1MGLLFAAHCYP3A4 | |
| SCHEMBL11435388 | 0.81 | PHGDH (0.54) | PHGDHALDH1A1MGLLFAAHCYP3A4 | |
| SCHEMBL6832485 | 0.81 | PHGDH (0.48) | PHGDHALDH1A1MGLLFAAHLMNA | |
| SCHEMBL3072501 | 0.80 | PHGDH (0.58) | PHGDHALDH1A1MGLLFAAHCYP3A4 | |
| SCHEMBL40978 | 0.78 | PHGDH (0.56) | PHGDHALDH1A1MGLLFAAHCYP3A4 | |
| SCHEMBL1001644 | 0.78 | PHGDH (0.62) | PHGDHALDH1A1MGLLFAAHCYP3A4 | |
| SCHEMBL2828938 | 0.78 | PHGDH (0.56) | PHGDHALDH1A1MGLLFAAHCYP3A4 | |
| SCHEMBL17710528 | 0.77 | PHGDH (0.48) | PHGDHALDH1A1MGLLFAAHADH1A | |
| SCHEMBL17710504 | 0.77 | PHGDH (0.48) | PHGDHALDH1A1MGLLFAAHADH1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5019611-A | Tetrahydrotriazinethiones | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1991-05-28 | — | — | US | disclosed |