Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 9/20 | 0.51 |
| ▸ | GPBAR1 | Q8TDU6 | 5/20 | 0.44 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11335609 | 0.86 | ELANE (0.48) | ELANEGPBAR1 | |
| SCHEMBL10568991 | 0.84 | ELANE (0.55) | ELANEGPBAR1 | |
| SCHEMBL11001445 | 0.83 | ELANE (0.46) | ELANEGPBAR1 | |
| SCHEMBL9870437 | 0.79 | ELANE (0.57) | ELANEGPBAR1 | |
| SCHEMBL11063454 | 0.76 | ELANE (0.45) | ELANEHTR2C | |
| SCHEMBL9870404 | 0.73 | ELANE (0.46) | ELANEGPBAR1 | |
| SCHEMBL11269741 | 0.73 | ELANE (0.57) | ELANEGPBAR1HTR2C | |
| SCHEMBL11046224 | 0.72 | ELANE (0.56) | ELANEGPBAR1HTR2C | |
| SCHEMBL11275712 | 0.72 | ELANE (0.56) | ELANEGPBAR1 | |
| SCHEMBL11274179 | 0.71 | ELANE (0.60) | ELANEGPBAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5021566-A | Carbapenicillins; preservatives; antiseptics; grampositive and gram negative bacteria | MERCK & CO. INC. (US) | 1991-06-04 | — | — | US | disclosed |
| US-4745188-A | ANTIBIOTICS, SULFIDING | MERCK & CO., INC. (US) | 1988-05-17 | — | — | US | disclosed |
| US-4707547-A | AMINATION TO FORM ANTIBIOTIC | MERCK & CO., INC. (US) | 1987-11-17 | — | — | US | disclosed |
| US-4530841-A | Antibiotic containing hetero ring | MERCK & CO., INC. (US) | 1985-07-23 | — | — | US | disclosed |