Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2957850 | 0.79 | MAPK1 (0.54) | MAPK1 | |
| Hydrochloric Acid SCHEMBL2957846 | 0.77 | MAPK1 (0.52) | MAPK1 | |
| SCHEMBL854108 | 0.72 | TSHR (0.36) | — | |
| SCHEMBL20187194 | 0.72 | TSHR (0.42) | — | |
| SCHEMBL12436684 | 0.71 | OGFRL1 (0.39) | — | |
| SCHEMBL852148 | 0.71 | OGFRL1 (0.39) | — | |
| SCHEMBL15858210 | 0.71 | OGFRL1 (0.39) | — | |
| SCHEMBL16743555 | 0.71 | OGFRL1 (0.39) | — | |
| SCHEMBL15466791 | 0.71 | OGFRL1 (0.39) | — | |
| SCHEMBL1846733 | 0.71 | OGFRL1 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5017582-A | Analgesics | SANDOZ LTD. (CH) | 1991-05-21 | — | — | US | disclosed |
| US-4910207-A | Antipsychotic agent | NOVARTIS AG (CH) | 1990-03-20 | — | — | US | disclosed |
| US-4803199-A | SEROTONIN ANTAGONIST, ANALGESIC ANTIARRHYTHMIC AGENTS | NOVARTIS AG (CH) | 1989-02-07 | — | — | US | disclosed |