Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PREP | P48147 | 5/20 | 0.76 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | KLK7 | P49862 | 1/20 | 0.52 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.52 |
| ▸ | GFER | P55789 | 1/20 | 0.51 |
| ▸ | CTSK | P43235 | 1/20 | 0.51 |
| ▸ | PRCP | P42785 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9872924 | 1.00 | PREP (0.76) | PREPTSHRL3MBTL1KDM4ELMNA | |
| SCHEMBL9872921 | 1.00 | PREP (0.76) | PREPTSHRL3MBTL1KDM4ELMNA | |
| SCHEMBL9872401 | 0.91 | PREP (0.61) | PREPTSHRL3MBTL1KDM4ELMNA | |
| SCHEMBL9872394 | 0.91 | PREP (0.61) | PREPTSHRL3MBTL1KDM4ELMNA | |
| SCHEMBL7301658 | 0.90 | PREP (0.70) | PREPTSHRL3MBTL1KDM4ELMNA | |
| SCHEMBL7301666 | 0.90 | PREP (0.70) | PREPTSHRL3MBTL1KDM4ELMNA | |
| SCHEMBL7302338 | 0.88 | PREP (0.67) | PREPTSHRL3MBTL1KDM4ELMNA | |
| SCHEMBL7302343 | 0.88 | PREP (0.67) | PREPTSHRL3MBTL1KDM4ELMNA | |
| SCHEMBL9872359 | 0.87 | PREP (0.75) | PREPTSHRL3MBTL1KDM4ELMNA | |
| SCHEMBL9873052 | 0.87 | PREP (0.75) | PREPTSHRL3MBTL1KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5051444-A | Pyrrolidine derivatives as anti-amnesia agents | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1991-09-24 | — | — | US | disclosed |