SCHEMBL9873310

SCHEMBL9873310

CNC(=O)CCN1CCC(C(O)(c2ccc(F)cc2)c2ccccn2)CC1

nearest known ligand 0.49

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 4/20 0.49
PRCP P42785 6/20 0.48
CYP2J2 P51589 2/20 0.43
NPY2R P49146 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9873531 0.94 MEN1 (0.51) MEN1PRCPCYP2J2
SCHEMBL9874231 0.94 MEN1 (0.51) MEN1PRCPCYP2J2
SCHEMBL9873976 0.87 CYP2J2 (0.48) CYP2J2
SCHEMBL9873458 0.83 MEN1 (0.51) MEN1CYP2J2NPY2R
SCHEMBL9874473 0.83 MEN1 (0.51) MEN1CYP2J2NPY2R
SCHEMBL9873147 0.82 MEN1 (0.51) MEN1CYP2J2NPY2R
SCHEMBL9871858 0.82 CYP2J2 (0.58) CYP2J2
SCHEMBL9786921 0.82 MEN1 (0.57) MEN1CYP2J2
SCHEMBL9874017 0.81 CYP2J2 (0.51) CYP2J2
SCHEMBL10479198 0.81 MEN1 (0.56) MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5057524-A Asthma, dermatitis A. H. ROBINS COMPANY INCORPORATED (US) 1991-10-15 US disclosed