Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2J2 | P51589 | 6/20 | 0.61 |
| ▸ | HRH1 | P35367 | 8/20 | 0.58 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | CNR1 | P21554 | 1/20 | 0.47 |
| ▸ | APEX1 | P27695 | 1/20 | 0.47 |
| ▸ | PDE4A | P27815 | 1/20 | 0.47 |
| ▸ | HTR2A | P28223 | 1/20 | 0.47 |
| ▸ | DRD3 | P35462 | 1/20 | 0.47 |
| ▸ | HTR2B | P41595 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9871725 | 0.99 | CYP2J2 (0.60) | CYP2J2HRH1KCNH2LMNACNR1 | |
| SCHEMBL9874469 | 0.96 | CYP2J2 (0.65) | CYP2J2HRH1KCNH2LMNACNR1 | |
| SCHEMBL9872366 | 0.90 | CYP2J2 (0.51) | CYP2J2HRH1KCNH2LMNACNR1 | |
| SCHEMBL9874544 | 0.90 | CYP2J2 (0.51) | CYP2J2HRH1KCNH2LMNACNR1 | |
| SCHEMBL9873578 | 0.89 | CYP2J2 (0.62) | CYP2J2HRH1KCNH2LMNACNR1 | |
| SCHEMBL9873499 | 0.89 | CYP2J2 (0.50) | CYP2J2HRH1KCNH2LMNACNR1 | |
| SCHEMBL9873298 | 0.89 | CYP2J2 (0.50) | CYP2J2HRH1KCNH2LMNACNR1 | |
| SCHEMBL9874390 | 0.88 | CYP2J2 (0.61) | CYP2J2HRH1KCNH2LMNACNR1 | |
| SCHEMBL9873597 | 0.88 | CYP2J2 (0.63) | CYP2J2HRH1KCNH2 | |
| SCHEMBL9874107 | 0.87 | CYP2J2 (0.62) | CYP2J2HRH1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5057524-A | Asthma, dermatitis | A. H. ROBINS COMPANY INCORPORATED (US) | 1991-10-15 | — | — | US | disclosed |