Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PREP | P48147 | 1/20 | 0.57 |
| ▸ | FAP | Q12884 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | ACE | P12821 | 7/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | ACE2 | Q9BYF1 | 2/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9874715 | 1.00 | PREP (0.57) | PREPFAPALDH1A1MAPTMAPK1 | |
| SCHEMBL9874281 | 0.91 | PREP (0.59) | PREPFAPALDH1A1MAPTMAPK1 | |
| SCHEMBL9874283 | 0.91 | PREP (0.59) | PREPFAPALDH1A1MAPTMAPK1 | |
| SCHEMBL9874465 | 0.83 | PREP (0.59) | PREPFAPALDH1A1MAPTMAPK1 | |
| SCHEMBL9872028 | 0.83 | PREP (0.59) | PREPFAPALDH1A1MAPTMAPK1 | |
| SCHEMBL9873839 | 0.83 | PREP (0.62) | PREPFAPALDH1A1MAPTMAPK1 | |
| SCHEMBL9873842 | 0.83 | PREP (0.62) | PREPFAPALDH1A1MAPTMAPK1 | |
| SCHEMBL10557781 | 0.82 | PREP (0.60) | PREPFAPALDH1A1MAPTMAPK1 | |
| SCHEMBL9875166 | 0.82 | PREP (0.60) | PREPFAPALDH1A1MAPTMAPK1 | |
| SCHEMBL10776986 | 0.82 | PREP (0.55) | PREPFAPALDH1A1MAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5051444-A | Pyrrolidine derivatives as anti-amnesia agents | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1991-09-24 | — | — | US | disclosed |
| US-4880827-A | Pyrrolidine derivatives having inhibitory action for proline specific endopepidase | SUMITOMO PHARMACEUTICALS COMPANY, LTD. (JP) | 1989-11-14 | — | — | US | disclosed |
| EP-0238319-A1 | Pyrrolidine derivatives | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1987-09-23 | — | — | EP | disclosed |