Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDPK1 | O15530 | 2/20 | 0.63 |
| ▸ | MTOR | P42345 | 1/20 | 0.63 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | FUCA1 | P04066 | 1/20 | 0.41 |
| ▸ | SRC | P12931 | 1/20 | 0.39 |
| ▸ | CETP | P11597 | 3/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.36 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | ELANE | P08246 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13109573 | 0.98 | PDPK1 (0.65) | PDPK1MTORTSHRFUCA1SRC | |
| SCHEMBL5830234 | 0.98 | PDPK1 (0.65) | PDPK1MTORTSHRFUCA1SRC | |
| SCHEMBL13109619 | 0.97 | PDPK1 (0.68) | PDPK1MTORTSHRFUCA1SRC | |
| SCHEMBL7720528 | 0.95 | PDPK1 (0.65) | PDPK1MTORTSHRFUCA1SRC | |
| SCHEMBL14094690 | 0.89 | PDPK1 (0.73) | PDPK1MTORTSHRFUCA1SRC | |
| SCHEMBL5023249 | 0.89 | TSHR (0.55) | PDPK1MTORTSHRFUCA1SRC | |
| SCHEMBL5865737 | 0.88 | PDPK1 (0.82) | PDPK1MTORTSHR | |
| SCHEMBL5865550 | 0.88 | PDPK1 (0.82) | PDPK1MTORTSHR | |
| SCHEMBL4345266 | 0.86 | PDPK1 (0.61) | PDPK1MTORTSHRFUCA1SRC | |
| SCHEMBL4340900 | 0.86 | PDPK1 (0.61) | PDPK1MTORTSHRFUCA1SRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5055597-A | SYNTHESIS OF INOSITOL PHOSPHATES | MERCK SHARP & DOHME LTD. (GB) | 1991-10-08 | — | — | US | disclosed |
| US-4906761-A | Myo-inositol orthoformates | MERCK SHARPE & DOHME LTD. (GB) | 1990-03-06 | — | — | US | disclosed |