SCHEMBL9874267

SCHEMBL9874267

C=C(C)C(=O)OC(C)CNC(=O)OCC(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F

nearest known ligand 0.32

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9874275 0.82 TSHR (0.30) TSHR
SCHEMBL29827761 0.78 TSHR (0.34) TSHR
SCHEMBL1536934 0.77 TSHR (0.40) TSHR
SCHEMBL1536983 0.77 TSHR (0.40) TSHR
SCHEMBL632209 0.77 TSHR (0.40) TSHR
SCHEMBL36922 0.77 TSHR (0.40) TSHR
SCHEMBL1536958 0.77 TSHR (0.40) TSHR
SCHEMBL1536970 0.77 TSHR (0.40) TSHR
SCHEMBL1537175 0.77 TSHR (0.40) TSHR
SCHEMBL1536844 0.77 TSHR (0.40) TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4985473-A POLY/FLUOROOXYALKYLENE/URETHANES MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1991-01-15 US disclosed
EP-0040923-B1 COMPOSITIONS FOR PROVIDING ABHERENT COATINGS; POLY (FLUOROOYALKYLENE) URETHANE ACRYLATES MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1985-05-02 EP disclosed
US-4321404-A Compositions for providing abherent coatings MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1982-03-23 US disclosed
EP-0040923-A2 Compositions for providing abherent coatings; poly (fluorooyalkylene) urethane acrylates MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1981-12-02 EP disclosed