Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 0.51 |
| ▸ | CYP2J2 | P51589 | 5/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | HRH1 | P35367 | 2/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.42 |
| ▸ | FAAH | O00519 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9874459 | 1.00 | MEN1 (0.51) | MEN1CYP2J2KMT2AHRH1KCNH2 | |
| SCHEMBL9874030 | 0.89 | CYP2J2 (0.56) | CYP2J2HRH1KCNH2CYP3A4CYP2C9 | |
| SCHEMBL9873159 | 0.89 | CYP2J2 (0.56) | CYP2J2HRH1KCNH2CYP3A4CYP2C9 | |
| SCHEMBL9872280 | 0.89 | CYP2J2 (0.49) | CYP2J2HRH1KCNH2CYP3A4CYP2C9 | |
| SCHEMBL9871856 | 0.89 | CYP2J2 (0.49) | CYP2J2HRH1KCNH2CYP3A4CYP2C9 | |
| SCHEMBL9873618 | 0.89 | CYP2J2 (0.49) | CYP2J2HRH1KCNH2CYP3A4CYP2C9 | |
| SCHEMBL9873215 | 0.89 | CYP2J2 (0.49) | CYP2J2HRH1KCNH2CYP3A4CYP2C9 | |
| SCHEMBL9873261 | 0.89 | CYP2J2 (0.49) | CYP2J2HRH1KCNH2CYP3A4CYP2C9 | |
| SCHEMBL9786870 | 0.88 | CYP2J2 (0.50) | CYP2J2HRH1KCNH2CYP3A4CYP2C9 | |
| SCHEMBL9873147 | 0.88 | MEN1 (0.51) | MEN1CYP2J2KMT2AHRH1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5057524-A | Asthma, dermatitis | A. H. ROBINS COMPANY INCORPORATED (US) | 1991-10-15 | — | — | US | disclosed |