Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | CYP2J2 | P51589 | 6/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | RECQL | P46063 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 6/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | HRH1 | P35367 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9875216 | 0.94 | CYP2J2 (0.52) | CYP2J2MEN1KMT2AHRH1CYP2C9 | |
| SCHEMBL9874170 | 0.93 | MEN1 (0.49) | CYP2J2MEN1KMT2AHRH1CYP2C9 | |
| SCHEMBL9873976 | 0.86 | CYP2J2 (0.48) | ALDH1A1CYP2J2HTTRECQLNPSR1 | |
| SCHEMBL9874299 | 0.86 | HTT (0.60) | CYP2J2HTTRECQLNPSR1HRH1 | |
| SCHEMBL9871242 | 0.85 | MEN1 (0.53) | CYP2J2HTTRECQLNPSR1MEN1 | |
| SCHEMBL9874149 | 0.81 | CYP2J2 (0.61) | CYP2J2HRH1CYP2C9CYP3A4CYP2B6 | |
| SCHEMBL9871663 | 0.81 | CYP2J2 (0.52) | CYP2J2MEN1KMT2AHRH1CYP2C9 | |
| SCHEMBL9875059 | 0.80 | CYP2J2 (0.58) | CYP2J2HTTRECQLNPSR1MEN1 | |
| SCHEMBL9871858 | 0.80 | CYP2J2 (0.58) | CYP2J2HRH1CYP2C9CYP3A4CYP2B6 | |
| SCHEMBL9874649 | 0.80 | CYP2J2 (0.54) | CYP2J2MEN1KMT2AHRH1CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5057524-A | Asthma, dermatitis | A. H. ROBINS COMPANY INCORPORATED (US) | 1991-10-15 | — | — | US | disclosed |