Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Phenylethyl Alcohol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.70 |
| ▸ | TSHR | P16473 | 2/20 | 0.59 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA4 | P22748 | 1/20 | 0.44 |
| ▸ | CA6 | P23280 | 1/20 | 0.44 |
| ▸ | CA5A | P35218 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.44 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.44 |
| ▸ | CES2 | O00748 | 1/20 | 0.43 |
| ▸ | CES1 | P23141 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrocinnamyl Alcohol SCHEMBL9875250 | 0.88 | TDP1 (0.52) | TDP1TSHRCA2RAB9ASMN1; SMN2 | |
| Nitric Acid SCHEMBL9872446 | 0.86 | TDP1 (0.50) | TDP1TSHRCA2RAB9ASMN1; SMN2 | |
| Phenylethyl Alcohol SCHEMBL28820852 | 0.83 | TDP1 (1.00) | TDP1TSHRKEAP1CA2CA1 | |
| Phenylethyl Alcohol SCHEMBL8968173 | 0.83 | TDP1 (1.00) | TDP1TSHRKEAP1CA2CA1 | |
| Phenylethyl Alcohol SCHEMBL11450063 | 0.83 | TDP1 (1.00) | TDP1TSHRKEAP1CA2CA1 | |
| Phenylethyl Alcohol SCHEMBL1867158 | 0.83 | TDP1 (1.00) | TDP1TSHRKEAP1CA2CA1 | |
| Phenylethyl Alcohol SCHEMBL1838 | 0.83 | — | — | |
| Phenylethyl Alcohol SCHEMBL27927126 | 0.83 | TDP1 (1.00) | TDP1TSHRKEAP1CA2CA1 | |
| Benzyl Alcohol SCHEMBL2963501 | 0.82 | TSHR (0.67) | TDP1TSHRCA2CA12CA1 | |
| Phenylethyl Alcohol SCHEMBL14976669 | 0.81 | TDP1 (0.84) | TDP1TSHRKEAP1CA2CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5049694-A | Cardiovascular disorders | CEDONA PHARMACEUTICALS B.V. (NL) | 1991-09-17 | — | — | US | disclosed |
| EP-0359335-A2 | Pharmaceutical composition having relaxing activity which contains a nitrate ester as active substance | CEDONA PHARMACEUTICALS B.V. (NL) | 1990-03-21 | — | — | EP | disclosed |