Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2J2 | P51589 | 9/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.49 |
| ▸ | HTR1A | P08908 | 1/20 | 0.49 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.49 |
| ▸ | DRD1 | P21728 | 1/20 | 0.49 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.49 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.49 |
| ▸ | DRD3 | P35462 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.49 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.49 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.47 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9872366 | 0.97 | CYP2J2 (0.51) | CYP2J2CYP3A4CYP2C9CYP2B6DRD3 | |
| SCHEMBL9874355 | 0.96 | CYP2J2 (0.61) | CYP2J2CYP3A4CYP2C9CYP2B6DRD3 | |
| SCHEMBL9873499 | 0.95 | CYP2J2 (0.50) | CYP2J2CYP3A4CYP2C9CYP2B6DRD3 | |
| SCHEMBL9873350 | 0.93 | CYP2J2 (0.48) | CYP2J2CYP3A4CYP2C9CYP2B6DRD3 | |
| SCHEMBL9872538 | 0.92 | CYP2J2 (0.58) | CYP2J2CYP3A4CYP2C9CYP2B6DRD3 | |
| SCHEMBL9873332 | 0.92 | CYP2J2 (0.57) | CYP2J2CYP3A4CYP2C9CYP2B6DRD3 | |
| SCHEMBL9874469 | 0.89 | CYP2J2 (0.65) | CYP2J2CYP3A4CYP2C9CYP2B6DRD3 | |
| SCHEMBL9873141 | 0.88 | CYP2J2 (0.54) | CYP2J2CYP3A4CYP2C9CYP2B6DRD3 | |
| SCHEMBL9873117 | 0.88 | CYP2J2 (0.67) | CYP2J2CYP3A4CYP2C9CYP2B6KCNH2 | |
| SCHEMBL9873322 | 0.88 | CYP2J2 (0.49) | CYP2J2CYP3A4CYP2C9CYP2B6DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5057524-A | Asthma, dermatitis | A. H. ROBINS COMPANY INCORPORATED (US) | 1991-10-15 | — | — | US | disclosed |