Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 11/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | FNTB | P49356 | 3/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | HRH1 | P35367 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | FNTA | P49354 | 2/20 | 0.35 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.35 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9874507 | 1.00 | CYP19A1 (0.53) | CYP19A1KMT2ACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL2351745 | 0.89 | CYP19A1 (0.65) | CYP19A1CYP3A4CYP2C19SMN1; SMN2CYP11B1 | |
| SCHEMBL2351748 | 0.89 | CYP19A1 (0.65) | CYP19A1CYP3A4CYP2C19SMN1; SMN2CYP11B1 | |
| SCHEMBL2351752 | 0.89 | CYP19A1 (0.65) | CYP19A1CYP3A4CYP2C19SMN1; SMN2CYP11B1 | |
| SCHEMBL2353211 | 0.87 | CYP19A1 (0.55) | CYP19A1CYP3A4SMN1; SMN2 | |
| SCHEMBL2353212 | 0.87 | CYP19A1 (0.55) | CYP19A1CYP3A4SMN1; SMN2 | |
| SCHEMBL2353207 | 0.87 | CYP19A1 (0.55) | CYP19A1CYP3A4SMN1; SMN2 | |
| SCHEMBL2355442 | 0.84 | CYP19A1 (0.58) | CYP19A1MAPT | |
| SCHEMBL2355437 | 0.84 | CYP19A1 (0.58) | CYP19A1MAPT | |
| SCHEMBL2355438 | 0.84 | CYP19A1 (0.58) | CYP19A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5006543-A | Diphenylethane derivatives | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-04-09 | — | — | US | disclosed |