Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PI4KA | P42356 | 1/20 | 0.67 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.67 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.67 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.67 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.58 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.55 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.55 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.55 |
| ▸ | AMD1 | P17707 | 2/20 | 0.52 |
| ▸ | AHCY | P23526 | 4/20 | 0.47 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.46 |
| ▸ | WDR77 | Q9BQA1 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | DPP4 | P27487 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18009817 | 0.88 | PI4KA (0.69) | PI4KAPI4K2BPI4K2API4KBRXFP1 | |
| SCHEMBL18026181 | 0.88 | PI4KA (0.69) | PI4KAPI4K2BPI4K2API4KBRXFP1 | |
| SCHEMBL21413864 | 0.88 | PI4KA (0.69) | PI4KAPI4K2BPI4K2API4KBRXFP1 | |
| SCHEMBL5034920 | 0.88 | PI4KA (0.69) | PI4KAPI4K2BPI4K2API4KBRXFP1 | |
| SCHEMBL2291251 | 0.86 | PI4KA (0.63) | PI4KAPI4K2BPI4K2API4KBRXFP1 | |
| SCHEMBL28023791 | 0.84 | PI4KA (0.64) | PI4KAPI4K2BPI4K2API4KBRXFP1 | |
| SCHEMBL11408140 | 0.84 | PI4KA (0.64) | PI4KAPI4K2BPI4K2API4KBRXFP1 | |
| SCHEMBL1757325 | 0.84 | PI4KA (0.64) | PI4KAPI4K2BPI4K2API4KBRXFP1 | |
| SCHEMBL18127422 | 0.84 | PI4KA (0.72) | PI4KAPI4K2BPI4K2API4KBRXFP1 | |
| SCHEMBL11408135 | 0.83 | PI4KA (0.63) | PI4KAPI4K2BPI4K2API4KBRXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4997925-A | Enzyme inhibitors, viricides | MERRELL DOW PHARMACEUTICALS INC. (US) | 1991-03-05 | — | — | US | disclosed |