SCHEMBL9875431

SCHEMBL9875431

Oc1ccc2ccccc2c1-c1c(O)ccc2ccccc12.[Ti]

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTPN22 Q9Y2R2 1/20 0.62
POLB P06746 1/20 0.58
HSD17B10 Q99714 3/20 0.56
CYP1A2 P05177 2/20 0.56
USP2 O75604 1/20 0.56
PAK1 Q13153 1/20 0.56
CYP2C9 P11712 1/20 0.56
CYP2C19 P33261 1/20 0.56
ALDH1A1 P00352 3/20 0.52
TDP1 Q9NUW8 2/20 0.52
CYP2A6 P11509 1/20 0.52
TSHR P16473 1/20 0.52
MAPT P10636 3/20 0.52
KDM4E B2RXH2 3/20 0.52
GAA P10253 2/20 0.52
TAAR1 Q96RJ0 1/20 0.52
ERN1 O75460 1/20 0.52
NSD2 O96028 1/20 0.51
OPRM1 P35372 1/20 0.51
OPRD1 P41143 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL10748650 0.98 PTPN22 (0.67) PTPN22POLBHSD17B10CYP1A2USP2
SCHEMBL15400598 0.97 PTPN22 (0.65) PTPN22POLBHSD17B10CYP1A2USP2
SCHEMBL29027 0.97 PTPN22 (0.65) PTPN22POLBHSD17B10CYP1A2USP2
SCHEMBL29362162 0.97 PTPN22 (0.65) PTPN22POLBHSD17B10CYP1A2USP2
Charcoal, Activated SCHEMBL30539223 0.95 PTPN22 (0.62) PTPN22POLBHSD17B10CYP1A2USP2
SCHEMBL16291794 0.95 PTPN22 (0.62) PTPN22POLBHSD17B10CYP1A2USP2
Hydrogen Sulfide SCHEMBL30378374 0.95 PTPN22 (0.62) PTPN22POLBHSD17B10CYP1A2USP2
Methane SCHEMBL10406101 0.95 PTPN22 (0.62) PTPN22POLBHSD17B10CYP1A2USP2
Water SCHEMBL18660620 0.95 PTPN22 (0.62) PTPN22POLBHSD17B10CYP1A2USP2
SCHEMBL8381351 0.93 PTPN22 (0.60) PTPN22POLBHSD17B10CYP1A2USP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0241235-B1 PROCESS FOR THE PREPARATION OF HOMOALLYL ALCOHOLS ICI AUSTRALIA LIMITED (AU) 1991-02-27 EP claimed
US-4933511-A ORGANOMETALLIC CATALYSTS ICI AUSTRALIA LIMITED (AU) 1990-06-12 US claimed
EP-0241235-B1 PROCESS FOR THE PREPARATION OF HOMOALLYL ALCOHOLS ICI AUSTRALIA LIMITED (AU) 1991-02-27 EP disclosed
US-4933511-A ORGANOMETALLIC CATALYSTS ICI AUSTRALIA LIMITED (AU) 1990-06-12 US disclosed