Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMS | P04818 | 19/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6650039 | 0.94 | TYMS (0.61) | TYMSALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL6652207 | 0.86 | TYMS (0.57) | TYMSALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL6650779 | 0.78 | TYMS (0.62) | TYMSALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL6650191 | 0.76 | TYMS (1.00) | TYMS | |
| SCHEMBL6650227 | 0.76 | TYMS (0.59) | TYMSALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL6447534 | 0.75 | TYMS (0.56) | TYMSALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL6455693 | 0.74 | TYMS (0.46) | TYMSALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL6647960 | 0.73 | TYMS (0.58) | TYMSALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL6649923 | 0.72 | TYMS (0.59) | TYMSALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL6842333 | 0.72 | TYMS (1.00) | TYMS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991019700-A1 | PHARMACEUTICALLY ACTIVE BENZOQUINAZOLINE COMPOUNDS | THE WELLCOME FOUNDATION LIMITED (GB) | 1991-12-26 | — | — | WO | disclosed |