Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.73 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.73 |
| ▸ | TOP2A | P11388 | 6/20 | 0.59 |
| ▸ | TOP2B | Q02880 | 6/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.59 |
| ▸ | HPGD | P15428 | 4/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.59 |
| ▸ | ALB | P02768 | 1/20 | 0.59 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.59 |
| ▸ | AADAT | Q8N5Z0 | 2/20 | 0.58 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | TUBB | P07437 | 1/20 | 0.58 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.58 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.58 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.58 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.58 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.58 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.58 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9873382 | 0.91 | KDM4E (0.76) | KDM4EKMT2ATOP2ATOP2BALDH1A1 | |
| Hydrochloric Acid SCHEMBL9873544 | 0.90 | KDM4E (0.75) | KDM4EKMT2ATOP2ATOP2BALDH1A1 | |
| SCHEMBL21074648 | 0.86 | KDM4E (0.64) | KDM4EKMT2ATOP2ATOP2BALDH1A1 | |
| SCHEMBL21074776 | 0.85 | KDM4E (0.63) | KDM4EKMT2ATOP2ATOP2BALDH1A1 | |
| Pazufloxacin SCHEMBL21074686 | 0.85 | KDM4E (1.00) | KDM4EKMT2ATOP2ATOP2BALDH1A1 | |
| Pazufloxacin SCHEMBL8386358 | 0.85 | KDM4E (1.00) | KDM4EKMT2ATOP2ATOP2BALDH1A1 | |
| Pazufloxacin SCHEMBL29381001 | 0.85 | KDM4E (1.00) | KDM4EKMT2ATOP2ATOP2BALDH1A1 | |
| Pazufloxacin SCHEMBL34460 | 0.85 | KDM4E (1.00) | KDM4EKMT2ATOP2ATOP2BALDH1A1 | |
| SCHEMBL9873589 | 0.84 | KDM4E (0.62) | KDM4EKMT2ATOP2ATOP2BALDH1A1 | |
| SCHEMBL9874793 | 0.84 | KDM4E (0.77) | KDM4EKMT2ATOP2ATOP2BALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4990508-A | Reduced side effects | TOYAMA CHEMICAL CO., LTD. (JP) | 1991-02-05 | — | — | US | disclosed |