Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | IKBKB | O14920 | 2/20 | 0.43 |
| ▸ | CHUK | O15111 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.39 |
| ▸ | FEN1 | P39748 | 1/20 | 0.39 |
| ▸ | AXL | P30530 | 1/20 | 0.38 |
| ▸ | CDK8 | P49336 | 1/20 | 0.38 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.38 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9825748 | 0.92 | PARP10 (0.38) | NPC1IKBKBCHUKMEN1KMT2A | |
| SCHEMBL9825477 | 0.88 | IKBKB (0.51) | NPC1IKBKBCHUKMAPTALOX5AP | |
| SCHEMBL24034931 | 0.80 | AHR (0.46) | ADORA3NR3C1 | |
| SCHEMBL5661955 | 0.75 | GSTP1 (0.48) | NPC1IKBKBCHUKNR3C1 | |
| SCHEMBL7088348 | 0.75 | NPC1 (0.49) | NPC1IKBKBCHUKAXLCDK8 | |
| SCHEMBL594405 | 0.73 | AHR (0.50) | NPC1IKBKBCHUKMAPTTRPA1 | |
| SCHEMBL20232779 | 0.73 | IKBKB (0.55) | NPC1IKBKBCHUKAXLCDK8 | |
| SCHEMBL17573827 | 0.71 | IKBKB (0.50) | NPC1IKBKBCHUKALDH1A1HPGD | |
| SCHEMBL22178774 | 0.70 | NPC1 (0.61) | NPC1ALOX5APFEN1TRPA1MAP3K11 | |
| SCHEMBL31504070 | 0.70 | NPC1 (0.61) | NPC1ALOX5APFEN1TRPA1MAP3K11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5037575-A | Photostability | MITSUBISHI CHEMICAL INDUSTRIES LTD. (JP) | 1991-08-06 | — | — | US | disclosed |