Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.50 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | MC4R | P32245 | 1/20 | 0.50 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.50 |
| ▸ | MC3R | P41968 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.47 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6748574 | 0.81 | KDM4E (0.53) | BAZ2BADORA3TSHRMC4RADRA1A | |
| SCHEMBL14434128 | 0.81 | KDM4E (0.53) | BAZ2BADORA3TSHRMC4RADRA1A | |
| SCHEMBL6449733 | 0.77 | BAZ2B (0.57) | BAZ2BADORA3TSHRMC4RADRA1A | |
| SCHEMBL25154231 | 0.76 | KDM4E (0.44) | BAZ2BADORA3TSHRMC4RADRA1A | |
| SCHEMBL27923673 | 0.75 | — | — | |
| SCHEMBL5313214 | 0.75 | BAZ2B (0.46) | BAZ2BADORA3TSHRMC4RADRA1A | |
| SCHEMBL5313208 | 0.75 | BAZ2B (0.46) | BAZ2BADORA3TSHRMC4RADRA1A | |
| SCHEMBL940788 | 0.73 | HSP90AA1 (0.58) | BAZ2BADORA3TSHRMC4RADRA1A | |
| SCHEMBL940555 | 0.73 | HSP90AA1 (0.58) | BAZ2BADORA3TSHRMC4RADRA1A | |
| SCHEMBL14903392 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5049561-A | Anthelmintic acylhydrazones, method of use and compositions | THE UPJOHN COMPANY (US) | 1991-09-17 | — | — | US | claimed |
| EP-0370065-A1 | ANTHELMINTIC ACYLHYDRAZONES, METHOD OF USE AND COMPOSITIONS | THE UPJOHN COMPANY (US) | 1990-05-30 | — | — | EP | claimed |
| WO-1989000992-A1 | ANTHELMINTIC ACYLHYDRAZONES, METHOD OF USE AND COMPOSITIONS | THE UPJOHN COMPANY (US) | 1989-02-09 | — | — | WO | claimed |
| CN-110606843-B | Structure, preparation and application of bipyridyl ketone hydrazone-2-acetylpyrazine | 齐鲁工业大学 | 2022-10-21 | — | — | CN | disclosed |
| CN-110606843-A | Structure, preparation and application of bipyridone hydrazone-2-acetylpyrazine | 齐鲁工业大学 | 2019-12-24 | — | — | CN | disclosed |
| CN-110606843-A | Structure, preparation and application of bipyridone hydrazone-2-acetylpyrazine | 齐鲁工业大学 | 2019-12-24 | — | — | CN | disclosed |
| US-5049561-A | Anthelmintic acylhydrazones, method of use and compositions | THE UPJOHN COMPANY (US) | 1991-09-17 | — | — | US | disclosed |
| EP-0370065-A1 | ANTHELMINTIC ACYLHYDRAZONES, METHOD OF USE AND COMPOSITIONS | THE UPJOHN COMPANY (US) | 1990-05-30 | — | — | EP | disclosed |
| WO-1989000992-A1 | ANTHELMINTIC ACYLHYDRAZONES, METHOD OF USE AND COMPOSITIONS | THE UPJOHN COMPANY (US) | 1989-02-09 | — | — | WO | disclosed |