Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 3/20 | 0.55 |
| ▸ | KDM1A | O60341 | 1/20 | 0.49 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | PDE4A | P27815 | 1/20 | 0.40 |
| ▸ | SNCA | P37840 | 1/20 | 0.40 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.40 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.33 |
| ▸ | CDC25B | P30305 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | FNTA | P49354 | 1/20 | 0.31 |
| ▸ | FNTB | P49356 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9876588 | 1.00 | PTPN1 (0.55) | PTPN1KDM1APTGS1PDE4ASNCA | |
| SCHEMBL6907167 | 0.79 | PTPN1 (0.58) | PTPN1KDM1APTGS1PDE4ASNCA | |
| SCHEMBL6907169 | 0.79 | PTPN1 (0.58) | PTPN1KDM1APTGS1PDE4ASNCA | |
| SCHEMBL17824275 | 0.77 | PTPN1 (0.51) | PTPN1KDM1APTGS1PDE4ASNCA | |
| SCHEMBL17824276 | 0.77 | PTPN1 (0.51) | PTPN1KDM1APTGS1PDE4ASNCA | |
| SCHEMBL21558804 | 0.77 | PTPN1 (0.51) | PTPN1KDM1APTGS1PDE4ASNCA | |
| SCHEMBL163911 | 0.77 | PTPN1 (0.85) | PTPN1KDM1APTGS1PDE4ASNCA | |
| SCHEMBL27785652 | 0.77 | KDM1A (0.62) | PTPN1KDM1APTGS1PDE4ASNCA | |
| SCHEMBL163912 | 0.77 | PTPN1 (0.85) | PTPN1KDM1APTGS1PDE4ASNCA | |
| SCHEMBL23728386 | 0.75 | PTPN1 (0.58) | PTPN1KDM1APTGS1PDE4ASNCA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0254078-B1 | PYRAN DERIVATIVES | BASF Aktiengesellschaft (DE) | 1991-02-06 | — | — | EP | disclosed |
| EP-0254078-A1 | Pyran derivatives | BASF Aktiengesellschaft (DE) | 1988-01-27 | — | — | EP | disclosed |