Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.70 |
| ▸ | HPGD | P15428 | 1/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.67 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.63 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.61 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.61 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10719160 | 1.00 | POLB (0.70) | POLBHPGDSMN1; SMN2ABCB1CYP3A4 | |
| SCHEMBL10718691 | 0.92 | POLB (0.74) | POLBHPGDSMN1; SMN2ABCB1CYP3A4 | |
| SCHEMBL10722196 | 0.92 | POLB (0.74) | POLBHPGDSMN1; SMN2ABCB1CYP3A4 | |
| SCHEMBL10721968 | 0.89 | HPGD (0.66) | POLBHPGDSMN1; SMN2ABCB1CYP3A4 | |
| Hydrochloric Acid SCHEMBL8180457 | 0.88 | HPGD (0.64) | POLBHPGDSMN1; SMN2ABCB1CYP3A4 | |
| SCHEMBL10720152 | 0.87 | ABCB1 (0.70) | POLBHPGDSMN1; SMN2ABCB1CYP3A4 | |
| SCHEMBL9714554 | 0.87 | HPGD (0.89) | POLBHPGDSMN1; SMN2ABCB1CYP3A4 | |
| SCHEMBL8773650 | 0.87 | HPGD (0.89) | POLBHPGDSMN1; SMN2ABCB1CYP3A4 | |
| SCHEMBL10720191 | 0.84 | HPGD (0.63) | POLBHPGDSMN1; SMN2ABCB1CYP3A4 | |
| Rh-5849 SCHEMBL1538531 | 0.84 | POLB (1.00) | POLBHPGDSMN1; SMN2ABCB1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4985461-A | Insecticidal N'-substituted-N,N'-diacylhydrazines | ROHM AND HAAS COMPANY (US) | 1991-01-15 | — | — | US | disclosed |
| EP-0236618-A2 | Insecticidal N'-substituted-N,N'-diacylhydrazines | ROHM AND HAAS COMPANY (US) | 1987-09-16 | — | — | EP | disclosed |