Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LRRK2 | Q5S007 | 10/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | USP28 | Q96RU2 | 1/20 | 0.52 |
| ▸ | USP25 | Q9UHP3 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | PTGES | O14684 | 1/20 | 0.51 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL384896 | 0.88 | FOLH1 (0.68) | LRRK2KDM4EALDH1A1FOLH1HPGD | |
| SCHEMBL28260622 | 0.87 | LRRK2 (0.59) | LRRK2KDM4EALDH1A1FOLH1HPGD | |
| SCHEMBL6452235 | 0.84 | PTGDR2 (0.67) | LRRK2KDM4EALDH1A1FOLH1HPGD | |
| SCHEMBL30591972 | 0.84 | PTGDR2 (0.67) | LRRK2KDM4EALDH1A1FOLH1HPGD | |
| SCHEMBL4723723 | 0.84 | LRRK2 (0.58) | LRRK2KDM4EALDH1A1FOLH1HPGD | |
| SCHEMBL5627324 | 0.84 | LRRK2 (0.56) | LRRK2KDM4EALDH1A1FOLH1HPGD | |
| SCHEMBL552025 | 0.83 | LRRK2 (0.57) | LRRK2KDM4EALDH1A1FOLH1HPGD | |
| SCHEMBL6492975 | 0.82 | LRRK2 (0.60) | LRRK2KDM4EALDH1A1FOLH1HPGD | |
| SCHEMBL5627788 | 0.82 | LRRK2 (0.54) | LRRK2KDM4EALDH1A1FOLH1HPGD | |
| SCHEMBL5431545 | 0.82 | LRRK2 (0.63) | LRRK2KDM4EALDH1A1FOLH1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5017572-A | CALCIUM ANTAGONIST | DELALANDE S.A. (FR) | 1991-05-21 | — | — | US | disclosed |