SCHEMBL9877229

SCHEMBL9877229

CCCCC=C1OC(=O)N(c2cc(Cl)cc(Cl)c2)C1=O

nearest known ligand 0.38

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
KAT2B Q92831 1/20 0.33
TSHR P16473 1/20 0.33
HSD17B3 P37058 5/20 0.32
TRPA1 O75762 1/20 0.31
BCL2A1 Q16548 1/20 0.31
GRM2 Q14416 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9835675 0.81 BCL2A1 (0.37) BCL2A1
SCHEMBL9837006 0.72 BCL2A1 (0.38) TRPA1BCL2A1
SCHEMBL9867998 0.70 CFTR (0.37) TSHR
SCHEMBL11833534 0.69 TSHR (0.38) TSHRHSD17B3BCL2A1
SCHEMBL9877228 0.68 TSHR (0.36) TSHRBCL2A1
SCHEMBL9835991 0.65 TSHR (0.39) TSHRBCL2A1
SCHEMBL11540477 0.61 HSD17B10 (0.40) TSHRBCL2A1
SCHEMBL28015089 0.60 AHR (0.42)
SCHEMBL7788343 0.59 TYR (0.51) TSHRTRPA1
SCHEMBL7788402 0.59 TYR (0.51) TSHRTRPA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4983751-A Chemical intermediates SAGAMI CHEMICAL RESEARCH CENTER (JP) 1991-01-08 US disclosed
US-4818272-A NONPHYTOTOXICITY FOR CROPS HELICAL STREAMS SAGAMI CHEMICAL RESEARCH CENTER (JP) 1989-04-04 US disclosed
EP-0241559-A1 OXAZOLIDINEDIONE DERIVATIVES, PROCESS FOR THEIR PREPARATION, AND HERBICIDES CONTAINING THE SAME SAGAMI CHEMICAL RESEARCH CENTER (JP) 1987-10-21 EP disclosed