Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 5/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.45 |
| ▸ | APEX1 | P27695 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | RECQL | P46063 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | NR1I2 | O75469 | 4/20 | 0.44 |
| ▸ | ALB | P02768 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.44 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.44 |
| ▸ | SLC22A11 | Q9NSA0 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9877500 | 1.00 | PTGS1 (0.45) | PTGS1MAPTTDP1APEX1ALDH1A1 | |
| SCHEMBL9876881 | 0.93 | TDP1 (0.43) | PTGS1MAPTTDP1APEX1ALDH1A1 | |
| SCHEMBL9876883 | 0.93 | TDP1 (0.43) | PTGS1MAPTTDP1APEX1ALDH1A1 | |
| SCHEMBL9623995 | 0.91 | TDP1 (0.47) | PTGS1MAPTTDP1APEX1ALDH1A1 | |
| SCHEMBL9623998 | 0.91 | TDP1 (0.47) | PTGS1MAPTTDP1APEX1ALDH1A1 | |
| SCHEMBL9623944 | 0.89 | TDP1 (0.50) | PTGS1MAPTTDP1APEX1ALDH1A1 | |
| SCHEMBL9623946 | 0.89 | TDP1 (0.50) | PTGS1MAPTTDP1APEX1ALDH1A1 | |
| SCHEMBL9877497 | 0.85 | NR1I2 (0.54) | PTGS1MAPTTDP1APEX1ALDH1A1 | |
| SCHEMBL9877496 | 0.85 | NR1I2 (0.54) | PTGS1MAPTTDP1APEX1ALDH1A1 | |
| SCHEMBL9623627 | 0.84 | TDP1 (0.42) | PTGS1MAPTTDP1APEX1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4985555-A | MICROBIOCIDES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1991-01-15 | — | — | US | disclosed |
| US-4871730-A | MICROBIOCIDES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1989-10-03 | — | — | US | disclosed |
| EP-0268307-A2 | New starting compounds for cephem compounds and processes for their preparation | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1988-05-25 | — | — | EP | disclosed |
| EP-0133678-A2 | New cephem compounds, processes for preparation thereof and pharmaceutical compositions containing them | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1985-03-06 | — | — | EP | disclosed |