Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | PPARD | Q03181 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6623038 | 0.96 | PPARD (0.38) | TSHRPPARDTP53TDP1CA12 | |
| SCHEMBL814692 | 0.83 | MEN1 (0.37) | CYP3A4 | |
| SCHEMBL6579016 | 0.82 | TSHR (0.40) | TSHRPPARDTP53TDP1CA12 | |
| SCHEMBL2679555 | 0.80 | PPARD (0.39) | TSHRPPARDTP53TDP1CA12 | |
| SCHEMBL814225 | 0.79 | CYP3A4 (0.48) | TSHRCYP3A4 | |
| SCHEMBL4637563 | 0.79 | PPARD (0.35) | TSHRPPARDTP53TDP1CA12 | |
| SCHEMBL4550022 | 0.78 | PPARD (0.38) | TSHRPPARDTP53TDP1CA12 | |
| SCHEMBL98778 | 0.78 | PPARD (0.38) | TSHRPPARDTP53TDP1CA12 | |
| SCHEMBL5451688 | 0.78 | TP53 (0.39) | TSHRPPARDTP53TDP1CYP3A4 | |
| SCHEMBL7775440 | 0.78 | PPARD (0.38) | TSHRPPARDTP53TDP1CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 3317 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117304093-A | Piperidone alkaloid and analogues, synthesis method and application thereof | 暨南大学 | 2023-12-29 | — | — | CN | claimed |
| WO-2023243350-A1 | POLYCARBONATE RESIN COMPOSITION AND MOLDED ARTICLE COMPRISING SAME | 帝人株式会社 | 2023-12-21 | — | — | WO | claimed |
| WO-2023228768-A1 | THERMOPLASTIC RESIN COMPOSITION AND MOLDED ARTICLE FORMED FROM SAME | 帝人株式会社 | 2023-11-30 | — | — | WO | claimed |
| CN-111517932-B | Preparation method and intermediate of fused tricyclic derivative | 四川海思科制药有限公司 | 2023-03-24 | — | — | CN | claimed |
| US-20220274913-A1 | PROCESS FOR MANUFACTURING A SUBSTITUTED CYCLOHEXANECARBONITRILE | SOLVAY SA (BE) | 2022-09-01 | — | — | US | claimed |
| EP-4028383-A1 | PROCESS FOR MANUFACTURING A SUBSTITUTED CYCLOHEXANECARBONITRILE | SOLVAY SA (BE) | 2022-07-20 | — | — | EP | claimed |
| CN-112588448-B | Composite collecting agent and application thereof in chalcopyrite flotation | 中南大学 | 2021-12-14 | — | — | CN | claimed |
| CN-112588448-A | Composite collecting agent and application thereof in chalcopyrite flotation | 中南大学 | 2021-04-02 | — | — | CN | claimed |
| WO-2021048364-A1 | PROCESS FOR MANUFACTURING A SUBSTITUTED CYCLOHEXANECARBONITRILE | SOLVAY SA (BE) | 2021-03-18 | — | — | WO | claimed |
| CN-111517932-A | Preparation method and intermediate of fused tricyclic derivative | 四川海思科制药有限公司 | 2020-08-11 | — | — | CN | claimed |
| EP-0892774-A4 | PYRONIN ANTIBACTERIALS, PROCESS AND NOVEL INTERMEDIATES THERETO | ANADYS PHARMACEUTICALS INC (US) | 2001-10-04 | — | — | EP | claimed |
| US-6127551-A | 4-HYDROXY-6-ETHYOXYCARBONYLALKENYL-2H-PYRAN-2-ONE IS ACYLATED WITH PROPIONYL CHLORIDE TO FORM A KETONE ADDUCT, FOLLOWED BY BASE-CATALYZED ALDOL TO FROM A PYRONE ALDOL; MESYLATION, FORM A PYRONE KETONE; AND CURTIUS SEQUENCE TO FORM MYXOPYRONIN | SCRIPTGEN PHARMACEUTICALS, INC. (US) | 2000-10-03 | — | — | US | claimed |
| US-5986111-A | CONDENSATION OF ALDEHYDE WITH PYRONE TO FORM ADDUCT, OXIDATION AND SAPONIFICATION | SCRIPTGEN PHARMACEUTICALS, INC. (US) | 1999-11-16 | — | — | US | claimed |
| EP-0892774-A2 | PYRONIN ANTIBACTERIALS, PROCESS AND NOVEL INTERMEDIATES THERETO | SCRIPTGEN PHARMACEUTICALS, INC. (US) | 1999-01-27 | — | — | EP | claimed |
| WO-1997034569-A2 | PYRONIN ANTIBACTERIALS, PROCESS AND INTERMEDIATES | SCRIPTGEN PHARMACEUTICALS, INC. (US) | 1997-09-25 | — | — | WO | claimed |
| EP-0456932-B1 | Propanol derivatives and perfumes containing the same | TAKASAGO PERFUMERY CO LTD (JP) | 1995-01-18 | — | — | EP | claimed |
| EP-0293220-B1 | Pharmacologically active 2-and 3-substituted (1', 5'-diaryl-3-pyrazolyl)-N-Hydroxypropanamides and method for synthesizing | ORTHO PHARMA CORP (US) | 1994-08-31 | — | — | EP | claimed |
| EP-0396841-B1 | Fluorinated arachidonic acid derivatives | MERRELL DOW PHARMA (US) | 1994-02-02 | — | — | EP | claimed |
| US-4384126-A | Synthesis of deoxyzoapatanol derivatives | ORTHO PHARMACEUTICAL CORPORATION (US) | 1983-05-17 | — | — | US | claimed |
| US-4296035-A | Total synthesis of the utero-evacuant substance d,l-zoapatanol | ORTHO PHARMACEUTICAL CORPORATION (US) | 1981-10-20 | — | — | US | claimed |