Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.42 |
| ▸ | HRH1 | P35367 | 2/20 | 0.42 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 2/20 | 0.38 |
| ▸ | HTR1D | P28221 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | RAD52 | P43351 | 2/20 | 0.37 |
| ▸ | RECQL | P46063 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | GAPDH | P04406 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | APEX1 | P27695 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | HRH2 | P25021 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5268018 | 0.76 | KDM4E (0.46) | MAPK1MAPTNPSR1KDM4E | |
| SCHEMBL3141357 | 0.74 | KDM4E (0.41) | MAPTTDP1MEN1KMT2ACYP3A4 | |
| SCHEMBL2315045 | 0.73 | — | — | |
| SCHEMBL12603450 | 0.72 | TYR (0.42) | MAPTTDP1MEN1KMT2ACYP3A4 | |
| SCHEMBL13665461 | 0.71 | — | — | |
| SCHEMBL13992153 | 0.71 | NPSR1 (0.57) | NPSR1APEX1HSD17B10CYP2C19 | |
| SCHEMBL13970793 | 0.71 | SLC6A4 (0.43) | HTR2AHTR6 | |
| SCHEMBL10871517 | 0.67 | TAAR1 (0.54) | TAAR1MAPK1MAPTNPSR1HTR2A | |
| SCHEMBL18917027 | 0.67 | TAAR1 (0.62) | TAAR1HRH1HRH4MAPK1MAPT | |
| SCHEMBL21040111 | 0.67 | KDM4E (0.39) | HSD17B10KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0213326-B1 | 2,5-DIMETHYL PYRROLE DERIVATIVES, THEIR PREPARATION AND THEIR USE | CASSELLA Aktiengesellschaft (DE) | 1991-03-06 | — | — | EP | disclosed |