Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CG | P48736 | 2/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | GSK3B | P49841 | 3/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | PIM1 | P11309 | 1/20 | 0.37 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.37 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.37 |
| ▸ | TTR | P02766 | 1/20 | 0.36 |
| ▸ | PRF1 | P14222 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | NAT1 | P18440 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | GLS | O94925 | 1/20 | 0.35 |
| ▸ | GLS2 | Q9UI32 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10480790 | 0.87 | MAPT (0.34) | PPARAMEN1KMT2AHPGD | |
| SCHEMBL9721300 | 0.84 | NPC1 (0.41) | PIK3CGKCNH2GSK3BPPARATDP1 | |
| SCHEMBL9721298 | 0.84 | NPC1 (0.41) | PIK3CGKCNH2GSK3BPPARATDP1 | |
| SCHEMBL10480774 | 0.82 | MGAM (0.40) | PIK3CGKCNH2HPGD | |
| SCHEMBL10365461 | 0.79 | HPGD (0.51) | PIM1PIM2HPGD | |
| SCHEMBL10365459 | 0.79 | HPGD (0.51) | PIM1PIM2HPGD | |
| SCHEMBL9721205 | 0.77 | HRH3 (0.42) | PIK3CGKCNH2PPARATDP1MEN1 | |
| SCHEMBL9721203 | 0.77 | HRH3 (0.42) | PIK3CGKCNH2PPARATDP1MEN1 | |
| SCHEMBL9878492 | 0.75 | KDM4E (0.40) | PPARAHPGD | |
| SCHEMBL9721220 | 0.75 | MEN1 (0.41) | KCNH2PPARATDP1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991003474-A1 | HYPOGLYCEMIC THIAZOLIDINEDIONE DERIVATIVES | PFIZER INC. (US) | 1991-03-21 | — | — | WO | disclosed |