Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 5/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | PDE2A | O00408 | 1/20 | 0.30 |
| ▸ | PDE1A | P54750 | 1/20 | 0.30 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.30 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.30 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.30 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.30 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.30 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.30 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9266594 | 0.73 | CYP19A1 (0.61) | CYP19A1CYP11B1CYP11B2 | |
| SCHEMBL9192364 | 0.73 | CYP19A1 (0.61) | CYP19A1CYP11B1CYP11B2 | |
| SCHEMBL9267605 | 0.73 | CYP19A1 (0.61) | CYP19A1CYP11B1CYP11B2 | |
| SCHEMBL9194557 | 0.73 | CYP19A1 (0.61) | CYP19A1CYP11B1CYP11B2 | |
| SCHEMBL9194268 | 0.73 | CYP19A1 (0.61) | CYP19A1CYP11B1CYP11B2 | |
| Hydrochloric Acid SCHEMBL9316765 | 0.72 | CYP19A1 (0.60) | CYP19A1CYP11B1CYP11B2 | |
| SCHEMBL9196678 | 0.71 | CYP19A1 (0.59) | CYP19A1CYP11B1CYP11B2 | |
| SCHEMBL2355254 | 0.70 | CYP19A1 (0.38) | CYP19A1MAPTCYP11B1CYP11B2 | |
| SCHEMBL9192916 | 0.69 | CYP19A1 (0.59) | CYP19A1CYP11B1CYP11B2 | |
| SCHEMBL9823868 | 0.68 | IDO1 (0.45) | TDP1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991001975-A1 | CYCLOALKYLENAZOLES, PROCESS FOR PREPARING THEM, PHARMACEUTICAL PREPARATIONS CONTAINING THEM AND THEIR USE TO MANUFACTURE DRUGS | SCHERING AKTIENGESELLSCHAFT BERLIN UND BERGKAMEN (DE) | 1991-02-21 | — | — | WO | claimed |