Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
| ▸ | G6PC1 | P35575 | 1/20 | 0.42 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.41 |
| ▸ | CNR2 | P34972 | 3/20 | 0.40 |
| ▸ | CNR1 | P21554 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | TAS2R14 | Q9NYV8 | 2/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9518503 | 0.98 | SLC6A2 (0.46) | SLC6A2SLC6A4SLC6A3G6PC1AOC3 | |
| SCHEMBL28980138 | 0.92 | AOC3 (0.47) | SLC6A2SLC6A4SLC6A3G6PC1AOC3 | |
| SCHEMBL9737481 | 0.90 | AOC3 (0.45) | SLC6A2SLC6A4SLC6A3AOC3CNR2 | |
| Hydrochloric Acid SCHEMBL9458170 | 0.88 | CYP1A2 (0.50) | SLC6A2SLC6A4SLC6A3AOC3CNR2 | |
| Hydrochloric Acid SCHEMBL9518394 | 0.88 | AOC3 (0.44) | SLC6A2SLC6A4SLC6A3AOC3CNR2 | |
| SCHEMBL544819 | 0.85 | AOC3 (0.56) | AOC3CNR2MEN1KMT2ATSHR | |
| Hydrochloric Acid SCHEMBL4825334 | 0.83 | AOC3 (0.54) | AOC3MEN1KMT2ATSHR | |
| SCHEMBL9737153 | 0.81 | GBA1 (0.41) | AOC3LMNATAAR1CYP19A1MEN1 | |
| SCHEMBL934572 | 0.81 | BCL2A1 (0.51) | AOC3CNR2CNR1POLBTAAR1 | |
| SCHEMBL9735994 | 0.81 | CNR2 (0.48) | AOC3CNR2CNR1LMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0234708-B1 | TETRAHYDROCARBAZOLE 1-ALKANOIC ACIDS | MERCK FROSST CANADA INC. (CA) | 1991-02-27 | — | — | EP | disclosed |
| EP-0300676-A2 | Tetrahydrocarbazole 1-alkanoic acids | MERCK FROSST CANADA INC. (CA) | 1989-01-25 | — | — | EP | disclosed |