SCHEMBL9879519

SCHEMBL9879519

CC(C)(C)c1cc(CCC(=O)NCCCO)cc(-n2nc3ccccc3n2)c1O

nearest known ligand 0.53

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.53
MEN1 O00255 1/20 0.53
GAA P10253 6/20 0.52
MAOB P27338 3/20 0.50
MAOA P21397 2/20 0.50
ACHE P22303 1/20 0.50
LMNA P02545 3/20 0.41
ALDH1A1 P00352 2/20 0.41
AGTR1 P30556 1/20 0.41
HTT P42858 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
GSK3B P49841 2/20 0.40
HPGD P15428 2/20 0.39
KDM4E B2RXH2 2/20 0.38
MAPT P10636 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8160946 0.94 KMT2A (0.55) KMT2AMEN1GAAMAOBMAOA
SCHEMBL14577857 0.92 KMT2A (0.51) KMT2AMEN1GAAMAOBMAOA
SCHEMBL14157762 0.91 KMT2A (0.48) KMT2AMEN1GAAMAOBMAOA
SCHEMBL9879512 0.90 KMT2A (0.55) KMT2AMEN1GAAMAOBMAOA
SCHEMBL7749752 0.90 KMT2A (0.55) KMT2AMEN1GAAMAOBMAOA
SCHEMBL14577846 0.90 GAA (0.54) KMT2AMEN1GAAMAOBMAOA
SCHEMBL14577829 0.90 KMT2A (0.51) KMT2AMEN1GAAMAOBMAOA
SCHEMBL9326704 0.89 KMT2A (0.54) KMT2AMEN1GAAMAOBMAOA
SCHEMBL13871632 0.89 KMT2A (0.50) KMT2AMEN1GAAMAOBMAOA
SCHEMBL14157763 0.89 KMT2A (0.50) KMT2AMEN1GAAMAOBMAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5032498-A Soluble stabilizers CIBA-GEIGY CORPORATION (US) 1991-07-16 US disclosed
US-4973702-A AMIDES AND ESTERS, UV STABILIZERS FOR PLASTICS AND PHOTOGRAPHIC MATERIALS CIBA-GEIGY CORPORATION (US) 1990-11-27 US disclosed
US-4892915-A Copolymers of 2-(2-hydroxy-5-acryloyloxyalkyl)phenyl-2H-benzotriazoles CIBA-GEIGY CORPORATION (US) 1990-01-09 US disclosed
US-4853471-A 2-(2-Hydroxyphenyl)-benztriazoles, their use as UV-absorbers and their preparation CIBA-GEIGY CORPORATION (US) 1989-08-01 US disclosed
EP-0133164-B1 COMPOUNDS WHICH CAN BE COPOLYMERISED CIBA-GEIGY AG (CH) 1988-12-14 EP disclosed
US-4785063-A LIGHT STABILIZERS CIBA-GEIGY CORPORATION (US) 1988-11-15 US disclosed
EP-0057160-B1 2-(2-HYDROXYPHENYL)-BENZOTRIAZOLES, THEIR USE AS ULTRAVIOLET STABILIZERS AND THEIR PREPARATION CIBA-GEIGY AG (CH) 1985-06-19 EP disclosed
EP-0133164-A2 Compounds which can be copolymerised CIBA-GEIGY AG (CH) 1985-02-13 EP disclosed