Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | TDP2 | O95551 | 1/20 | 0.31 |
| ▸ | NSD2 | O96028 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | GALK1 | P51570 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3854510 | 0.75 | KDM4E (0.37) | KDM4EATMLMNAHTT | |
| SCHEMBL5800131 | 0.75 | TNF (0.34) | KDM4EATMLMNAHTTPOLB | |
| SCHEMBL9531 | 0.72 | ATM (0.48) | ATM | |
| SCHEMBL7900240 | 0.70 | HTT (0.42) | KDM4EATMLMNAHTTPOLB | |
| Water SCHEMBL5786021 | 0.70 | ATM (0.46) | ATM | |
| Hydrochloric Acid SCHEMBL7370284 | 0.70 | BCHE (0.50) | — | |
| SCHEMBL3730208 | 0.68 | ATM (0.40) | ATMLMNAHTTMAPT | |
| SCHEMBL14742904 | 0.67 | ATM (0.54) | KDM4EATMLMNAHTTMAPT | |
| SCHEMBL7102910 | 0.67 | ATM (0.33) | KDM4EATMLMNAHTTTDP1 | |
| SCHEMBL13979159 | 0.66 | HTT (0.39) | KDM4EATMLMNAHTTTDP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4996204-A | Antidiabetic agents | PFIZER INC. (US) | 1991-02-26 | — | — | US | disclosed |