Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.42 |
| ▸ | HTR2B | P41595 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | HTR1B | P28222 | 1/20 | 0.40 |
| ▸ | THRA | P10827 | 2/20 | 0.39 |
| ▸ | THRB | P10828 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10490480 | 0.87 | MEN1 (0.51) | ALDH1A1TLR8MEN1NR1I2LMNA | |
| SCHEMBL9879726 | 0.82 | PTPN1 (0.42) | ALDH1A1TLR8MEN1NR1I2LMNA | |
| SCHEMBL27490636 | 0.81 | MEN1 (0.49) | ALDH1A1TLR8MEN1NR1I2LMNA | |
| SCHEMBL27910856 | 0.81 | MEN1 (0.49) | ALDH1A1TLR8MEN1NR1I2LMNA | |
| SCHEMBL27913097 | 0.81 | MEN1 (0.49) | ALDH1A1TLR8MEN1NR1I2LMNA | |
| SCHEMBL9879678 | 0.81 | PTPN1 (0.42) | ALDH1A1TLR8MEN1NR1I2LMNA | |
| SCHEMBL12589669 | 0.80 | MEN1 (0.46) | ALDH1A1TLR8MEN1NR1I2LMNA | |
| SCHEMBL25229294 | 0.79 | NPC1 (0.53) | KCNH2 | |
| SCHEMBL25227860 | 0.79 | NPC1 (0.53) | KCNH2 | |
| SCHEMBL25224593 | 0.79 | NPC1 (0.53) | KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4981612-A | AZO DYES | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-01-01 | — | — | US | disclosed |
| US-4946629-A | Optical element having non-linear optical properties including a substrate having a coating of an azo compound | IMPERIAL CHEMICAL INDUSTRIES, PLC (GB) | 1990-08-07 | — | — | US | disclosed |