Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 3/20 | 0.46 |
| ▸ | RARA | P10276 | 1/20 | 0.41 |
| ▸ | RARG | P13631 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 5/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.39 |
| ▸ | NPC1 | O15118 | 4/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.39 |
| ▸ | RELA | Q04206 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.36 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.36 |
| ▸ | CTRC | Q99895 | 1/20 | 0.36 |
| ▸ | BRS3 | P32247 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9155955 | 0.97 | RARB (0.48) | RARBRARARARGRAB9ASMN1; SMN2 | |
| SCHEMBL9159847 | 0.95 | RARB (0.41) | RARBRARARARGRAB9ASMN1; SMN2 | |
| SCHEMBL9156850 | 0.94 | RARB (0.53) | RARBRARARARGRAB9ASMN1; SMN2 | |
| SCHEMBL9158183 | 0.93 | RARB (0.55) | RARBRARARARGRAB9ASMN1; SMN2 | |
| SCHEMBL9159010 | 0.93 | RARB (0.55) | RARBRARARARGRAB9ASMN1; SMN2 | |
| SCHEMBL9873704 | 0.93 | RARB (0.55) | RARBRARARARGRAB9ASMN1; SMN2 | |
| SCHEMBL9162398 | 0.84 | MAPT (0.39) | RAB9AL3MBTL1MAPTAKR1C3AKR1C2 | |
| SCHEMBL12760412 | 0.84 | RARB (0.57) | RARBRARARARGHSD17B10MAPT | |
| SCHEMBL17359399 | 0.84 | RARB (0.57) | RARBRARARARGHSD17B10MAPT | |
| SCHEMBL14175165 | 0.84 | RARB (0.57) | RARBRARARARGHSD17B10MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991004248-A1 | PYRIDINE DERIVATIVES | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 1991-04-04 | — | — | WO | disclosed |