Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 10/20 | 0.51 |
| ▸ | HRH1 | P35367 | 5/20 | 0.46 |
| ▸ | HTR2A | P28223 | 5/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 5/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 4/20 | 0.46 |
| ▸ | DRD2 | P14416 | 4/20 | 0.46 |
| ▸ | ADRA2B | P18089 | 4/20 | 0.46 |
| ▸ | ADRA2C | P18825 | 4/20 | 0.46 |
| ▸ | CHRM3 | P20309 | 4/20 | 0.46 |
| ▸ | HTR2C | P28335 | 4/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 4/20 | 0.46 |
| ▸ | DRD3 | P35462 | 4/20 | 0.46 |
| ▸ | OPRK1 | P41145 | 4/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.46 |
| ▸ | SMPD1 | P17405 | 3/20 | 0.46 |
| ▸ | SLC22A1 | O15245 | 3/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL221187 | 0.82 | SLC6A4 (0.68) | SLC6A4HRH1HTR2ASLC6A2CHRM1 | |
| Iodide SCHEMBL10598664 | 0.75 | SLC6A4 (0.52) | SLC6A4HRH1HTR2ASLC6A2CHRM1 | |
| SCHEMBL8728501 | 0.72 | SLC6A4 (0.51) | SLC6A4HRH1HTR2ASLC6A2CHRM1 | |
| SCHEMBL218473 | 0.71 | SLC6A4 (0.66) | SLC6A4HRH1HTR2ASLC6A2CHRM1 | |
| SCHEMBL26967791 | 0.71 | SLC6A4 (0.69) | SLC6A4HRH1HTR2ASLC6A2CHRM1 | |
| SCHEMBL9011097 | 0.71 | SLC6A4 (0.56) | SLC6A4HRH1HTR2ASLC6A2CHRM1 | |
| SCHEMBL8726952 | 0.71 | SLC6A4 (0.49) | SLC6A4HRH1HTR2ASLC6A2CHRM1 | |
| SCHEMBL29843225 | 0.71 | SLC6A4 (0.61) | SLC6A4HRH1HTR2ASLC6A2CHRM1 | |
| SCHEMBL220948 | 0.71 | SLC6A4 (0.61) | SLC6A4HRH1HTR2ASLC6A2CHRM1 | |
| SCHEMBL8724668 | 0.71 | SLC6A4 (0.61) | SLC6A4HRH1HTR2ASLC6A2CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5017566-A | Redox systems for brain-targeted drug delivery | UNIVERSITY OF FLORIDA (US) | 1991-05-21 | — | — | US | claimed |