Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMS | P04818 | 12/20 | 0.54 |
| ▸ | FPGS | Q05932 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | PPARD | Q03181 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6447643 | 0.90 | TYMS (0.56) | TYMSFPGS | |
| SCHEMBL6446417 | 0.90 | TYMS (0.64) | TYMS | |
| SCHEMBL6446398 | 0.90 | TYMS (0.64) | TYMS | |
| SCHEMBL9422204 | 0.86 | TYMS (0.57) | TYMS | |
| SCHEMBL6651090 | 0.82 | TYMS (0.48) | TYMSFPGS | |
| SCHEMBL6648735 | 0.82 | TYMS (0.58) | TYMS | |
| SCHEMBL6447490 | 0.81 | TYMS (0.61) | TYMS | |
| SCHEMBL6842975 | 0.79 | TYMS (0.53) | TYMS | |
| SCHEMBL6447640 | 0.78 | TYMS (0.52) | TYMS | |
| SCHEMBL9422199 | 0.77 | TYMS (0.55) | TYMS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991019700-A1 | PHARMACEUTICALLY ACTIVE BENZOQUINAZOLINE COMPOUNDS | THE WELLCOME FOUNDATION LIMITED (GB) | 1991-12-26 | — | — | WO | disclosed |