SCHEMBL9883299

SCHEMBL9883299

N#Cc1nc2c3nc(N)c(N)nc3c3nc(N)c(N)nc3c2nc1N

nearest known ligand 0.39

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
USP8 P40818 1/20 0.39
CSNK1A1 P48729 1/20 0.30
CLK4 Q9HAZ1 1/20 0.30
ALDH1A1 P00352 1/20 0.30
KDM4E B2RXH2 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12263080 1.00 USP8 (0.39) USP8CSNK1A1CLK4ALDH1A1KDM4E
SCHEMBL12324918 1.00 USP8 (0.39) USP8CSNK1A1CLK4ALDH1A1KDM4E
SCHEMBL19484668 1.00 USP8 (0.39) USP8CSNK1A1CLK4ALDH1A1KDM4E
SCHEMBL13355976 0.97 USP8 (0.38) USP8ALDH1A1KDM4E
SCHEMBL19751843 0.97 USP8 (0.38) USP8ALDH1A1KDM4E
SCHEMBL20036425 0.97 USP8 (0.40) USP8CSNK1A1CLK4ALDH1A1KDM4E
SCHEMBL24263905 0.95 USP8 (0.39) USP8CSNK1A1CLK4ALDH1A1KDM4E
SCHEMBL20651248 0.95 USP8 (0.39) USP8CSNK1A1CLK4ALDH1A1KDM4E
SCHEMBL2606234 0.95 USP8 (0.39) USP8CSNK1A1CLK4ALDH1A1KDM4E
SCHEMBL14681740 0.95 USP8 (0.39) USP8CSNK1A1CLK4ALDH1A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3843171-B1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORP (US) 2023-09-27 EP disclosed
EP-4141010-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES Universal Display Corporation (US) 2023-03-01 EP disclosed
EP-3323822-B1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORP (US) 2019-08-28 EP disclosed
EP-3444260-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES Universal Display Corporation (US) 2019-02-20 EP disclosed
EP-3435438-A2 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES Universal Display Corporation (US) 2019-01-30 EP disclosed
EP-3056504-B1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORP (US) 2018-07-11 EP disclosed
EP-3301088-A1 CONDENSED PYRIDINES AS ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES Universal Display Corporation (US) 2018-04-04 EP disclosed
EP-3297051-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES Universal Display Corporation (US) 2018-03-21 EP disclosed
WO-2012069121-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2012-05-31 WO disclosed
WO-2012016630-A1 MATERIALS FOR ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2012-02-09 WO disclosed
WO-2011116869-A1 COMPOUNDS FOR ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2011-09-29 WO disclosed
WO-2011057701-A1 ORGANIC COMPOUNDS FOR ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2011-05-19 WO disclosed
WO-2011050888-A1 MATERIALS FOR ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2011-05-05 WO disclosed