Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 3/20 | 0.37 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | HTR7 | P34969 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9100697 | 0.91 | HRH3 (0.39) | DRD4 | |
| SCHEMBL9103026 | 0.91 | HRH3 (0.39) | DRD4 | |
| SCHEMBL9100703 | 0.91 | HRH3 (0.39) | DRD4 | |
| SCHEMBL9102725 | 0.88 | CHRM2 (0.41) | SIGMAR1 | |
| SCHEMBL9102709 | 0.88 | CHRM2 (0.41) | SIGMAR1 | |
| SCHEMBL9103204 | 0.88 | CHRM2 (0.39) | SIGMAR1MAOAMAOB | |
| SCHEMBL9103197 | 0.88 | CHRM2 (0.39) | SIGMAR1MAOAMAOB | |
| SCHEMBL9105132 | 0.88 | DRD4 (0.39) | DRD4TMEM97SIGMAR1MEN1KMT2A | |
| SCHEMBL9105136 | 0.88 | DRD4 (0.39) | DRD4TMEM97SIGMAR1MEN1KMT2A | |
| SCHEMBL9100700 | 0.87 | DRD4 (0.37) | DRD4TMEM97SIGMAR1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012074469-A1 | NEW IKACH BLOCKERS | ASTRAZENECA AB (SE) | 2012-06-07 | — | — | WO | disclosed |