Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNP | P00491 | 17/20 | 0.62 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.56 |
| ▸ | MTAP | Q13126 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15318133 | 0.85 | PNP (0.64) | PNPHPRT1MTAP | |
| SCHEMBL9888106 | 0.81 | PNP (0.73) | PNPHPRT1MTAP | |
| SCHEMBL9888108 | 0.79 | PNP (0.76) | PNPHPRT1MTAP | |
| Forodesine SCHEMBL15740309 | 0.78 | PNP (1.00) | PNPHPRT1 | |
| Forodesine SCHEMBL15740194 | 0.78 | PNP (1.00) | PNPHPRT1 | |
| Forodesine SCHEMBL21386033 | 0.78 | PNP (1.00) | PNPHPRT1 | |
| Forodesine SCHEMBL15373311 | 0.78 | PNP (1.00) | PNPHPRT1 | |
| Forodesine SCHEMBL15318145 | 0.78 | PNP (1.00) | PNPHPRT1 | |
| Forodesine SCHEMBL3896676 | 0.78 | PNP (1.00) | PNPHPRT1 | |
| Forodesine SCHEMBL2292668 | 0.78 | PNP (1.00) | PNPHPRT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9290501-B2 | Methods, assays and compounds for treating bacterial infections by inhibiting methylthioinosine phosphorylase | ALBERT EINSTEIN COLLEGE OF MEDICINE, INC. (US) | 2016-03-22 | — | — | US | disclosed |
| US-20130274220-A1 | METHODS, ASSAYS AND COMPOUNDS FOR TREATING BACTERIAL INFECTIONS BY INHIBITING METHYLTHIOINOSINE PHOSPHORYLASE | INDUSTRIAL RESEARCH LIMITED (NZ) | 2013-10-17 | — | — | US | disclosed |
| WO-2012074912-A1 | METHODS, ASSAYS AND COMPOUNDS FOR TREATING BACTERIAL INFECTIONS BY INHIBITING METHYLTHIOINOSINE PHOSPHORYLASE | ALBERT EINSTEIN COLLEGE OF MEDICINE OF YESHIVA UNIVERSITY (US) | 2012-06-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130274220-A1 | METHODS, ASSAYS AND COMPOUNDS FOR TREATING BACTERIAL INFECTIONS BY INHIBITING METHYLTHIOINOSINE PHOSPHORYLASE | MTAP, MPG, MTMR1 | PNP 14/4885HPRT1 106/4885MTAP 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.