Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM5 | P08912 | 2/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | FUCA1 | P04066 | 1/20 | 0.31 |
| ▸ | MGAM | O43451 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | SI | P14410 | 1/20 | 0.30 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9888340 | 1.00 | CHRM5 (0.31) | CHRM5CHRM1CHRM3CHRM2CHRM4 | |
| SCHEMBL10477558 | 0.81 | FUCA1 (0.37) | CHRM5CHRM1CHRM3CHRM2CHRM4 | |
| SCHEMBL10477567 | 0.81 | FUCA1 (0.37) | CHRM5CHRM1CHRM3CHRM2CHRM4 | |
| SCHEMBL7352844 | 0.80 | MGAM (0.31) | MGAMGAASIMGAM2 | |
| SCHEMBL19891156 | 0.76 | — | — | |
| SCHEMBL14882862 | 0.75 | — | — | |
| SCHEMBL14883078 | 0.74 | CA1 (0.39) | CHRM5CHRM1CHRM3CHRM2CHRM4 | |
| SCHEMBL29347457 | 0.73 | — | — | |
| SCHEMBL9787225 | 0.73 | — | — | |
| SCHEMBL23097490 | 0.72 | CHRM5 (0.35) | CHRM5CHRM1CHRM3CHRM2CHRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012074547-A2 | STEROID COMPOUNDS AS RORγt MODULATORS AND USES THEREOF | NEW YORK UNIVERSITY (US) | 2012-06-07 | — | — | WO | disclosed |