SCHEMBL9890048

SCHEMBL9890048

c1ccc(-c2cc(-n3c4ccccc4c4cc5oc6ccccc6c5cc43)cc(-n3c4ccccc4c4cc5oc6ccccc6c5cc43)c2)cc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.41
ATM Q13315 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
AHR P35869 2/20 0.40
MEN1 O00255 4/20 0.36
ALDH1A1 P00352 4/20 0.36
KMT2A Q03164 4/20 0.36
HPGD P15428 3/20 0.36
MAPT P10636 3/20 0.36
SMN1; SMN2 Q16637 3/20 0.36
NPC1 O15118 2/20 0.36
RAB9A P51151 2/20 0.36
GABRP O00591 1/20 0.34
GABRD O14764 1/20 0.34
CA12 O43570 1/20 0.34
TNKS O95271 1/20 0.34
CA1 P00915 1/20 0.34
CA2 P00918 1/20 0.34
TP53 P04637 1/20 0.34
ABCB1 P08183 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9890045 0.97 KDM4E (0.41) KDM4EATML3MBTL1AHRMEN1
SCHEMBL17245953 0.97 KDM4E (0.41) KDM4EATML3MBTL1AHRMEN1
SCHEMBL17245955 0.96 KDM4E (0.40) KDM4EATML3MBTL1AHRMEN1
SCHEMBL17245956 0.95 KDM4E (0.39) KDM4EATML3MBTL1AHRMEN1
SCHEMBL19071408 0.95 KDM4E (0.41) KDM4EATML3MBTL1AHRMEN1
SCHEMBL9889946 0.95 KDM4E (0.41) KDM4EATML3MBTL1AHRMEN1
SCHEMBL24676400 0.94 KDM4E (0.41) KDM4EATML3MBTL1AHRMEN1
SCHEMBL17071023 0.94 KDM4E (0.38) KDM4EATML3MBTL1AHRMEN1
SCHEMBL24676093 0.93 KDM4E (0.40) KDM4EATML3MBTL1AHRMEN1
SCHEMBL17300000 0.92 KDM4E (0.44) KDM4EATML3MBTL1AHRMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120138915-A1 ORGANIC ELECTROLUMINESCENCE DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2012-06-07 US disclosed
US-20120138915-A1 ORGANIC ELECTROLUMINESCENCE DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2012-06-07 US disclosed